Buprenophine
Buprenophine Brand names, Buprenophine Analogs
Buprenophine Brand Names Mixture
- No information avaliable
Buprenophine Chemical_Formula
C29H41NO4
Buprenophine RX_link
http://www.rxlist.com/cgi/generic3/suboxone.htm
Buprenophine fda sheet
Buprenophine msds (material safety sheet)
Buprenophine Synthesis Reference
No information avaliable
Buprenophine Molecular Weight
467.64 g/mol
Buprenophine Melting Point
No information avaliable
Buprenophine H2O Solubility
No information avaliable
Buprenophine State
Solid
Buprenophine LogP
5.096
Buprenophine Dosage Forms
Tablet (sublingual)
Buprenophine Indication
For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.
Buprenophine Pharmacology
Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Buprenophine Absorption
31% bioavailability (sublingual)
Buprenophine side effects and Toxicity
Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.
Buprenophine Patient Information
Buprenophine Organisms Affected
Humans and other mammals
