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Buprenophine Brand names, Buprenophine Analogs

Buprenophine Brand Names Mixture

  • No information avaliable

Buprenophine Chemical_Formula


Buprenophine RX_link


Buprenophine fda sheet

Buprenophine FDA

Buprenophine msds (material safety sheet)

Buprenophine Synthesis Reference

No information avaliable

Buprenophine Molecular Weight

467.64 g/mol

Buprenophine Melting Point

No information avaliable

Buprenophine H2O Solubility

No information avaliable

Buprenophine State


Buprenophine LogP


Buprenophine Dosage Forms

Tablet (sublingual)

Buprenophine Indication

For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.

Buprenophine Pharmacology

Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.

Buprenophine Absorption

31% bioavailability (sublingual)

Buprenophine side effects and Toxicity

Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.

Buprenophine Patient Information

Buprenophine Organisms Affected

Humans and other mammals