Temgesic
Temgesic Brand names, Temgesic Analogs
Temgesic Brand Names Mixture
- No information avaliable
Temgesic Chemical_Formula
C29H41NO4
Temgesic RX_link
http://www.rxlist.com/cgi/generic3/suboxone.htm
Temgesic fda sheet
Temgesic msds (material safety sheet)
Temgesic Synthesis Reference
No information avaliable
Temgesic Molecular Weight
467.64 g/mol
Temgesic Melting Point
No information avaliable
Temgesic H2O Solubility
No information avaliable
Temgesic State
Solid
Temgesic LogP
5.096
Temgesic Dosage Forms
Tablet (sublingual)
Temgesic Indication
For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.
Temgesic Pharmacology
Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Temgesic Absorption
31% bioavailability (sublingual)
Temgesic side effects and Toxicity
Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.
Temgesic Patient Information
Temgesic Organisms Affected
Humans and other mammals
