Buprenex
Buprenex Brand names, Buprenex Analogs
Buprenex Brand Names Mixture
- No information avaliable
Buprenex Chemical_Formula
C29H41NO4
Buprenex RX_link
http://www.rxlist.com/cgi/generic3/suboxone.htm
Buprenex fda sheet
Buprenex msds (material safety sheet)
Buprenex Synthesis Reference
No information avaliable
Buprenex Molecular Weight
467.64 g/mol
Buprenex Melting Point
No information avaliable
Buprenex H2O Solubility
No information avaliable
Buprenex State
Solid
Buprenex LogP
5.096
Buprenex Dosage Forms
Tablet (sublingual)
Buprenex Indication
For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.
Buprenex Pharmacology
Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Buprenex Absorption
31% bioavailability (sublingual)
Buprenex side effects and Toxicity
Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.
Buprenex Patient Information
Buprenex Organisms Affected
Humans and other mammals
