Buprenorphine Hcl en es it fr

Buprenorphine Hcl Brand names, Buprenorphine Hcl Analogs

Buprenorphine Hcl Brand Names Mixture

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Buprenorphine Hcl Chemical_Formula


Buprenorphine Hcl RX_link


Buprenorphine Hcl fda sheet

Buprenorphine_Hcl FDA

Buprenorphine Hcl msds (material safety sheet)

Buprenorphine Hcl Synthesis Reference

No information avaliable

Buprenorphine Hcl Molecular Weight

467.64 g/mol

Buprenorphine Hcl Melting Point

No information avaliable

Buprenorphine Hcl H2O Solubility

No information avaliable

Buprenorphine Hcl State


Buprenorphine Hcl LogP


Buprenorphine Hcl Dosage Forms

Tablet (sublingual)

Buprenorphine Hcl Indication

For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.

Buprenorphine Hcl Pharmacology

Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.

Buprenorphine Hcl Absorption

31% bioavailability (sublingual)

Buprenorphine Hcl side effects and Toxicity

Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.

Buprenorphine Hcl Patient Information

Buprenorphine Hcl Organisms Affected

Humans and other mammals