Buprenorphine Hcl
Buprenorphine Hcl Brand names, Buprenorphine Hcl Analogs
Buprenorphine Hcl Brand Names Mixture
- No information avaliable
Buprenorphine Hcl Chemical_Formula
C29H41NO4
Buprenorphine Hcl RX_link
http://www.rxlist.com/cgi/generic3/suboxone.htm
Buprenorphine Hcl fda sheet
Buprenorphine Hcl msds (material safety sheet)
Buprenorphine Hcl Synthesis Reference
No information avaliable
Buprenorphine Hcl Molecular Weight
467.64 g/mol
Buprenorphine Hcl Melting Point
No information avaliable
Buprenorphine Hcl H2O Solubility
No information avaliable
Buprenorphine Hcl State
Solid
Buprenorphine Hcl LogP
5.096
Buprenorphine Hcl Dosage Forms
Tablet (sublingual)
Buprenorphine Hcl Indication
For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.
Buprenorphine Hcl Pharmacology
Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Buprenorphine Hcl Absorption
31% bioavailability (sublingual)
Buprenorphine Hcl side effects and Toxicity
Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.
Buprenorphine Hcl Patient Information
Buprenorphine Hcl Organisms Affected
Humans and other mammals
