Subutex
Subutex Brand names, Subutex Analogs
Subutex Brand Names Mixture
- No information avaliable
Subutex Chemical_Formula
C29H41NO4
Subutex RX_link
http://www.rxlist.com/cgi/generic3/suboxone.htm
Subutex fda sheet
Subutex msds (material safety sheet)
Subutex Synthesis Reference
No information avaliable
Subutex Molecular Weight
467.64 g/mol
Subutex Melting Point
No information avaliable
Subutex H2O Solubility
No information avaliable
Subutex State
Solid
Subutex LogP
5.096
Subutex Dosage Forms
Tablet (sublingual)
Subutex Indication
For the treatment of moderate to severe pain, peri-operative analgesia, and opioid dependence.
Subutex Pharmacology
Buprenorphine is a synthetic opioid analgesic and thebaine derivative, with a longer duration of action than morphine. Buprenorphine interacts predominately with the opioid mu-receptor. These mu-binding sites are discretely distributed in the human brain, spinal cord, and other tissues. In clinical settings, buprenorphine exerts its principal pharmacologic effects on the central nervous system. Its primary actions of therapeutic value are analgesia and sedation. Buprenorphine may increase the patient's tolerance for pain and decrease the perception of suffering, although the presence of the pain itself may still be recognized. In addition to analgesia, alterations in mood, euphoria and dysphoria, and drowsiness commonly occur. Buprenorphine depresses the respiratory centers, depresses the cough reflex, and constricts the pupils.
Subutex Absorption
31% bioavailability (sublingual)
Subutex side effects and Toxicity
Manifestations of acute overdose include pinpoint pupils, sedation, hypotension, respiratory depression and death.
Subutex Patient Information
Subutex Organisms Affected
Humans and other mammals
