Zinecard
Category
Zinecard Brand names, Zinecard Analogs
Zinecard Brand Names Mixture
Zinecard Chemical_Formula
C11H16N4O4
Zinecard RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Zinecard fda sheet
Zinecard msds (material safety sheet)
Zinecard Synthesis Reference
No information avaliable
Zinecard Molecular Weight
268.269 g/mol
Zinecard Melting Point
191 - 197 oC
Zinecard H2O Solubility
Sparingly soluble
Zinecard State
Solid
Zinecard LogP
-2.135
Zinecard Dosage Forms
Liquid; Powder for solution
Zinecard Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Zinecard Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Zinecard Absorption
IV administration results in complete bioavailability.
Zinecard side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Zinecard Patient Information
No information avaliable
Zinecard Organisms Affected
Humans and other mammals
