Tepirone
Category
Tepirone Brand names, Tepirone Analogs
Tepirone Brand Names Mixture
Tepirone Chemical_Formula
C11H16N4O4
Tepirone RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Tepirone fda sheet
Tepirone msds (material safety sheet)
Tepirone Synthesis Reference
No information avaliable
Tepirone Molecular Weight
268.269 g/mol
Tepirone Melting Point
191 - 197 oC
Tepirone H2O Solubility
Sparingly soluble
Tepirone State
Solid
Tepirone LogP
-2.135
Tepirone Dosage Forms
Liquid; Powder for solution
Tepirone Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Tepirone Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Tepirone Absorption
IV administration results in complete bioavailability.
Tepirone side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Tepirone Patient Information
No information avaliable
Tepirone Organisms Affected
Humans and other mammals
