Eucardion
Category
Eucardion Brand names, Eucardion Analogs
Eucardion Brand Names Mixture
Eucardion Chemical_Formula
C11H16N4O4
Eucardion RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Eucardion fda sheet
Eucardion msds (material safety sheet)
Eucardion Synthesis Reference
No information avaliable
Eucardion Molecular Weight
268.269 g/mol
Eucardion Melting Point
191 - 197 oC
Eucardion H2O Solubility
Sparingly soluble
Eucardion State
Solid
Eucardion LogP
-2.135
Eucardion Dosage Forms
Liquid; Powder for solution
Eucardion Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Eucardion Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Eucardion Absorption
IV administration results in complete bioavailability.
Eucardion side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Eucardion Patient Information
No information avaliable
Eucardion Organisms Affected
Humans and other mammals
