Cardioxane
Category
Cardioxane Brand names, Cardioxane Analogs
Cardioxane Brand Names Mixture
Cardioxane Chemical_Formula
C11H16N4O4
Cardioxane RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Cardioxane fda sheet
Cardioxane msds (material safety sheet)
Cardioxane Synthesis Reference
No information avaliable
Cardioxane Molecular Weight
268.269 g/mol
Cardioxane Melting Point
191 - 197 oC
Cardioxane H2O Solubility
Sparingly soluble
Cardioxane State
Solid
Cardioxane LogP
-2.135
Cardioxane Dosage Forms
Liquid; Powder for solution
Cardioxane Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Cardioxane Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Cardioxane Absorption
IV administration results in complete bioavailability.
Cardioxane side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Cardioxane Patient Information
No information avaliable
Cardioxane Organisms Affected
Humans and other mammals
