Troxozone
Category
Troxozone Brand names, Troxozone Analogs
Troxozone Brand Names Mixture
Troxozone Chemical_Formula
C11H16N4O4
Troxozone RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Troxozone fda sheet
Troxozone msds (material safety sheet)
Troxozone Synthesis Reference
No information avaliable
Troxozone Molecular Weight
268.269 g/mol
Troxozone Melting Point
191 - 197 oC
Troxozone H2O Solubility
Sparingly soluble
Troxozone State
Solid
Troxozone LogP
-2.135
Troxozone Dosage Forms
Liquid; Powder for solution
Troxozone Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Troxozone Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Troxozone Absorption
IV administration results in complete bioavailability.
Troxozone side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Troxozone Patient Information
No information avaliable
Troxozone Organisms Affected
Humans and other mammals
