Dyzoxane
Category
Dyzoxane Brand names, Dyzoxane Analogs
Dyzoxane Brand Names Mixture
Dyzoxane Chemical_Formula
C11H16N4O4
Dyzoxane RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Dyzoxane fda sheet
Dyzoxane msds (material safety sheet)
Dyzoxane Synthesis Reference
No information avaliable
Dyzoxane Molecular Weight
268.269 g/mol
Dyzoxane Melting Point
191 - 197 oC
Dyzoxane H2O Solubility
Sparingly soluble
Dyzoxane State
Solid
Dyzoxane LogP
-2.135
Dyzoxane Dosage Forms
Liquid; Powder for solution
Dyzoxane Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Dyzoxane Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Dyzoxane Absorption
IV administration results in complete bioavailability.
Dyzoxane side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Dyzoxane Patient Information
No information avaliable
Dyzoxane Organisms Affected
Humans and other mammals
