Razoxin
Category
Razoxin Brand names, Razoxin Analogs
Razoxin Brand Names Mixture
Razoxin Chemical_Formula
C11H16N4O4
Razoxin RX_link
http://www.rxlist.com/cgi/generic2/dexrazoxane.htm
Razoxin fda sheet
Razoxin msds (material safety sheet)
Razoxin Synthesis Reference
No information avaliable
Razoxin Molecular Weight
268.269 g/mol
Razoxin Melting Point
191 - 197 oC
Razoxin H2O Solubility
Sparingly soluble
Razoxin State
Solid
Razoxin LogP
-2.135
Razoxin Dosage Forms
Liquid; Powder for solution
Razoxin Indication
For reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer.
Razoxin Pharmacology
Dexrazoxane is a cardioprotective agent for use in conjunction with doxorubicin indicated for reducing the incidence and severity of cardiomyopathy associated with doxorubicin administration in women with metastatic breast cancer who have received a cumulative doxorubicin dose.
Razoxin Absorption
IV administration results in complete bioavailability.
Razoxin side effects and Toxicity
Intraperitoneal, mouse LD10 = 500 mg/kg. Intravenous, dog LD10 = 2 gm/kg.
Razoxin Patient Information
No information avaliable
Razoxin Organisms Affected
Humans and other mammals
