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Candex Brand names, Candex Analogs

Candex Brand Names Mixture

  • No information avaliable

Candex Chemical_Formula

C47H75NO17

Candex RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Candex fda sheet

Candex FDA

Candex msds (material safety sheet)

Candex MSDS

Candex Synthesis Reference

No information avaliable

Candex Molecular Weight

926.09 g/mol

Candex Melting Point

160oC

Candex H2O Solubility

360 mg/L

Candex State

Solid

Candex LogP

-0.534

Candex Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Candex Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Candex Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Candex Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Candex side effects and Toxicity

No information avaliable

Candex Patient Information

No information avaliable

Candex Organisms Affected

Fungi