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Pedi-Dri Brand names, Pedi-Dri Analogs

Pedi-Dri Brand Names Mixture

  • No information avaliable

Pedi-Dri Chemical_Formula

C47H75NO17

Pedi-Dri RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Pedi-Dri fda sheet

Pedi-Dri FDA

Pedi-Dri msds (material safety sheet)

Pedi-Dri MSDS

Pedi-Dri Synthesis Reference

No information avaliable

Pedi-Dri Molecular Weight

926.09 g/mol

Pedi-Dri Melting Point

160oC

Pedi-Dri H2O Solubility

360 mg/L

Pedi-Dri State

Solid

Pedi-Dri LogP

-0.534

Pedi-Dri Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Pedi-Dri Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Pedi-Dri Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Pedi-Dri Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Pedi-Dri side effects and Toxicity

No information avaliable

Pedi-Dri Patient Information

No information avaliable

Pedi-Dri Organisms Affected

Fungi