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Nadostine Brand names, Nadostine Analogs

Nadostine Brand Names Mixture

  • No information avaliable

Nadostine Chemical_Formula

C47H75NO17

Nadostine RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Nadostine fda sheet

Nadostine FDA

Nadostine msds (material safety sheet)

Nadostine MSDS

Nadostine Synthesis Reference

No information avaliable

Nadostine Molecular Weight

926.09 g/mol

Nadostine Melting Point

160oC

Nadostine H2O Solubility

360 mg/L

Nadostine State

Solid

Nadostine LogP

-0.534

Nadostine Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Nadostine Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Nadostine Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Nadostine Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Nadostine side effects and Toxicity

No information avaliable

Nadostine Patient Information

No information avaliable

Nadostine Organisms Affected

Fungi