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Nilstat Brand names, Nilstat Analogs

Nilstat Brand Names Mixture

  • No information avaliable

Nilstat Chemical_Formula

C47H75NO17

Nilstat RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Nilstat fda sheet

Nilstat FDA

Nilstat msds (material safety sheet)

Nilstat MSDS

Nilstat Synthesis Reference

No information avaliable

Nilstat Molecular Weight

926.09 g/mol

Nilstat Melting Point

160oC

Nilstat H2O Solubility

360 mg/L

Nilstat State

Solid

Nilstat LogP

-0.534

Nilstat Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Nilstat Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Nilstat Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Nilstat Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Nilstat side effects and Toxicity

No information avaliable

Nilstat Patient Information

No information avaliable

Nilstat Organisms Affected

Fungi