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Mykinac Brand names, Mykinac Analogs

Mykinac Brand Names Mixture

  • No information avaliable

Mykinac Chemical_Formula

C47H75NO17

Mykinac RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Mykinac fda sheet

Mykinac FDA

Mykinac msds (material safety sheet)

Mykinac MSDS

Mykinac Synthesis Reference

No information avaliable

Mykinac Molecular Weight

926.09 g/mol

Mykinac Melting Point

160oC

Mykinac H2O Solubility

360 mg/L

Mykinac State

Solid

Mykinac LogP

-0.534

Mykinac Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Mykinac Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Mykinac Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Mykinac Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Mykinac side effects and Toxicity

No information avaliable

Mykinac Patient Information

No information avaliable

Mykinac Organisms Affected

Fungi