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Korostatin Brand names, Korostatin Analogs

Korostatin Brand Names Mixture

  • No information avaliable

Korostatin Chemical_Formula

C47H75NO17

Korostatin RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Korostatin fda sheet

Korostatin FDA

Korostatin msds (material safety sheet)

Korostatin MSDS

Korostatin Synthesis Reference

No information avaliable

Korostatin Molecular Weight

926.09 g/mol

Korostatin Melting Point

160oC

Korostatin H2O Solubility

360 mg/L

Korostatin State

Solid

Korostatin LogP

-0.534

Korostatin Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Korostatin Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Korostatin Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Korostatin Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Korostatin side effects and Toxicity

No information avaliable

Korostatin Patient Information

No information avaliable

Korostatin Organisms Affected

Fungi