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Nysert Brand names, Nysert Analogs

Nysert Brand Names Mixture

  • No information avaliable

Nysert Chemical_Formula

C47H75NO17

Nysert RX_link

http://www.rxlist.com/cgi/generic2/nystat.htm

Nysert fda sheet

Nysert FDA

Nysert msds (material safety sheet)

Nysert MSDS

Nysert Synthesis Reference

No information avaliable

Nysert Molecular Weight

926.09 g/mol

Nysert Melting Point

160oC

Nysert H2O Solubility

360 mg/L

Nysert State

Solid

Nysert LogP

-0.534

Nysert Dosage Forms

Cream; Drops; Liquid; Ointment; Suspension; Tablet

Nysert Indication

For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species

Nysert Pharmacology

Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.

Nysert Absorption

Nystatin is not absorbed from intact skin or mucous membrane

Nysert side effects and Toxicity

No information avaliable

Nysert Patient Information

No information avaliable

Nysert Organisms Affected

Fungi