Barstatin_100
Category
Barstatin_100 Brand names, Barstatin_100 Analogs
Barstatin_100 Brand Names Mixture
No information avaliable
Barstatin_100 Chemical_Formula
C47H75NO17
Barstatin_100 RX_link
http://www.rxlist.com/cgi/generic2/nystat.htm
Barstatin_100 fda sheet
Barstatin_100 msds (material safety sheet)
Barstatin_100 Synthesis Reference
No information avaliable
Barstatin_100 Molecular Weight
926.09 g/mol
Barstatin_100 Melting Point
160oC
Barstatin_100 H2O Solubility
360 mg/L
Barstatin_100 State
Solid
Barstatin_100 LogP
-0.534
Barstatin_100 Dosage Forms
Cream; Drops; Liquid; Ointment; Suspension; Tablet
Barstatin_100 Indication
For treatment of cutaneous or mucocutaneous mycotic infections caused by Candida species
Barstatin_100 Pharmacology
Nystatin is an antibiotic which is both fungistatic and fungicidal in vitro against a wide variety of yeasts and yeast-like fungi, including Candida albicans, C. parapsilosis, C. tropicalis, C. guilliermondi, C. pseudotropicalis, C. krusei, Torulopsis glabrata, Tricophyton rubrum, T. mentagrophytes. Nystatin acts by binding to sterols in the cell membrane of susceptible species resulting in a change in membrane permeability and the subsequent leakage of intracellular components. On repeated subculturing with increasing levels of nystatin, Candida albicans does not develop resistance to nystatin. Generally, resistance to nystatin does not develop during therapy. However, other species of Candida (C. tropicalis, C. guilliermondi, C. krusei, and C. stellatoides) become quite resistant on treatment with nystatin and simultaneously become cross resistant to amphotericin as well. This resistance is lost when the antibiotic is removed. Nystatin exhibits no appreciable activity against bacteria, protozoa, or viruses.
Barstatin_100 Absorption
Nystatin is not absorbed from intact skin or mucous membrane
Barstatin_100 Toxicity
No information avaliable
Barstatin_100 Patient Information
No information avaliable
Barstatin_100 Organisms Affected
Fungi
