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p-Hydroxyampicillin Brand names, p-Hydroxyampicillin Analogs

p-Hydroxyampicillin Brand Names Mixture

  • Co-amoxiclav (amoxicillin + clavulanic acid)
  • Augmentin (amoxicillin + clavulanic acid)
  • Prevpac (amoxicillin + clarithromycin + lansoprazole)

p-Hydroxyampicillin Chemical_Formula


p-Hydroxyampicillin RX_link


p-Hydroxyampicillin fda sheet

p-Hydroxyampicillin FDA

p-Hydroxyampicillin msds (material safety sheet)

p-Hydroxyampicillin MSDS

p-Hydroxyampicillin Synthesis Reference

Nayler, Smith, U.S. Pat. 3,192,198 (1965)

p-Hydroxyampicillin Molecular Weight

365.405 g/mol

p-Hydroxyampicillin Melting Point

194 oC

p-Hydroxyampicillin H2O Solubility

3430 mg/L

p-Hydroxyampicillin State


p-Hydroxyampicillin LogP


p-Hydroxyampicillin Dosage Forms

Capsule (250 mg or 500 mg); Powder for solution; Powder for suspension; Suspension; Tablet (500 mg or 875 mg)

p-Hydroxyampicillin Indication

For the treatment of infections of the ear, nose, and throat, the genitourinary tract, the skin and skin structure, and the lower respiratory tract due to susceptible (only b-lactamase-negative) strains of Streptococcus spp. (a- and b-hemolytic strains only), S. pneumoniae, Staphylococcus spp., H. influenzae, E. coli, P. mirabilis, or E. faecalis. Also for the treatment of acute, uncomplicated gonorrhea (ano-genital and urethral infections) due to N. gonorrhoeae (males and females).

p-Hydroxyampicillin Pharmacology

Amoxicillin is a moderate-spectrum antibiotic active against a wide range of Gram-positive, and a limited range of Gram-negative organisms. It is usually the drug of choice within the class because it is better absorbed, following oral administration, than other beta-lactam antibiotics. Amoxicillin is susceptible to degradation by β-lactamase-producing bacteria, and so may be given with clavulanic acid to increase its susceptability. The incidence of β-lactamase-producing resistant organisms, including E. coli, appears to be increasing. Amoxicillin is sometimes combined with clavulanic acid, a β-lactamase inhibitor, to increase the spectrum of action against Gram-negative organisms, and to overcome bacterial antibiotic resistance mediated through β-lactamase production.

p-Hydroxyampicillin Absorption

Rapidly absorbed after oral administration.

p-Hydroxyampicillin side effects and Toxicity

Serious toxicity is unlikely following large doses of amoxicillin. Acute ingestion of large doses of amoxicillin may cause nausea, vomiting, diarrhea and abdominal pain. Acute oliguric renal failure and hematuria may occur following large doses.

p-Hydroxyampicillin Patient Information

Amoxicillin is an antibiotic for treatment of infection.
Take at regular intervals, around the clock. Always finish course of therapy.
Take with or without meals.
May cause serious allergic reactions in those with penicillin allergy.
May cause nausea, vomiting and diarrhea; notify your doctor or pharmacist if these occur.

p-Hydroxyampicillin Organisms Affected

Enteric bacteria and other eubacteria