nafcillin sodium salt
Brand names,
nafcillin sodium salt
Analogs
nafcillin sodium salt
Brand Names Mixture
nafcillin sodium salt
Chemical_Formula
C33H47NO13
nafcillin sodium salt
RX_link
http://www.rxlist.com/cgi/generic2/natamycin.htm
nafcillin sodium salt
fda sheet
nafcillin sodium salt
msds (material safety sheet)
nafcillin sodium salt
Synthesis Reference
No information avaliable
nafcillin sodium salt
Molecular Weight
665.725 g/mol
nafcillin sodium salt
Melting Point
290 oC
nafcillin sodium salt
H2O Solubility
4100 mg/L
nafcillin sodium salt
State
Solid
nafcillin sodium salt
LogP
0.495
nafcillin sodium salt
Dosage Forms
Ophthalmic suspension (5%)
nafcillin sodium salt
Indication
For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.
nafcillin sodium salt
Pharmacology
Natamycin is an antifungal drug for topical ophthalmic administration. It is a tetraene polyene antibiotic derived from Streptomyces natalensis. It possesses in vitro activity against a variety of yeast and filamentous fungi, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium. Although the activity against fungi is dose-related, natamycin is predominantly fungicidal. Natamycin is not effective in vitro against gram-positive or gram-negative bacteria. Topical administration appears to produce effective concentrations of natamycin within the corneal stroma but not in intraocular fluid.
nafcillin sodium salt
Absorption
Systemic absorption should not be expected following topical administration, and as with other polyene antibiotics, absorption from the gastrointestinal tract is very poor.
nafcillin sodium salt
side effects and Toxicity
No information avaliable
nafcillin sodium salt
Patient Information
nafcillin sodium salt
Organisms Affected
Various Fungus Species