Nallpen In Plastic Container
Brand names,
Nallpen In Plastic Container
Analogs
Nallpen In Plastic Container
Brand Names Mixture
Nallpen In Plastic Container
Chemical_Formula
C33H47NO13
Nallpen In Plastic Container
RX_link
http://www.rxlist.com/cgi/generic2/natamycin.htm
Nallpen In Plastic Container
fda sheet
Nallpen In Plastic Container
msds (material safety sheet)
Nallpen In Plastic Container
Synthesis Reference
No information avaliable
Nallpen In Plastic Container
Molecular Weight
665.725 g/mol
Nallpen In Plastic Container
Melting Point
290 oC
Nallpen In Plastic Container
H2O Solubility
4100 mg/L
Nallpen In Plastic Container
State
Solid
Nallpen In Plastic Container
LogP
0.495
Nallpen In Plastic Container
Dosage Forms
Ophthalmic suspension (5%)
Nallpen In Plastic Container
Indication
For the treatment of fungal blepharitis, conjunctivitis, and keratitis caused by susceptible organisms including Fusarium solani keratitis.
Nallpen In Plastic Container
Pharmacology
Natamycin is an antifungal drug for topical ophthalmic administration. It is a tetraene polyene antibiotic derived from Streptomyces natalensis. It possesses in vitro activity against a variety of yeast and filamentous fungi, including Candida, Aspergillus, Cephalosporium, Fusarium and Penicillium. Although the activity against fungi is dose-related, natamycin is predominantly fungicidal. Natamycin is not effective in vitro against gram-positive or gram-negative bacteria. Topical administration appears to produce effective concentrations of natamycin within the corneal stroma but not in intraocular fluid.
Nallpen In Plastic Container
Absorption
Systemic absorption should not be expected following topical administration, and as with other polyene antibiotics, absorption from the gastrointestinal tract is very poor.
Nallpen In Plastic Container
side effects and Toxicity
No information avaliable
Nallpen In Plastic Container
Patient Information
Nallpen In Plastic Container
Organisms Affected
Various Fungus Species