Categorie
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Les marques,
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Analogs
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Les marques melange
No information avaliable
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Formule chimique
C8H6N4O5
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RX lien
http://www.rxlist.com/cgi/generic/nitro25m.htm
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FDA fiche
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msds (fiche de securite des materiaux)
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Synthese de reference
Aucune information disponible
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Poids moleculaire
238.157 g/mol
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Point de fusion
263 oC
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H2O Solubilite
79,5 mg / L
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Etat
Solid
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LogP
-0.04
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Formes pharmaceutiques
Tablet
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Indication
Pour le traitement de l'infection des voies urinaires
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Pharmacologie
Nitrofurantoin, un nitrofurane agent antibactérien, est disponible sous forme microcristalline et macrocristallin pour traiter les infections des voies urinaires causées par de nombreuses bactéries gram-négatives et certaines bactéries Gram-positives.
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Absorption
Aucune information disponible
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Toxicite
Aucune information disponible
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Information pour les patients
Patients should be advised to take Macrobid with food (ideally breakfast and dinner) to further
enhance tolerance and improve drug absorption. Patients should be instructed to complete the full course of therapy;
however, they should be advised to contact their physician if any unusual symptoms occur during therapy.
Patients should be advised not to use antacid preparations containing magnesium trisilicate while
taking Macrobid.
Patients should be counseled that antibacterial drugs including Macrobid should only be used to
treat bacterial infections. They do not treat viral infections (e.g., the common cold). When Macrobid is
prescribed to treat a bacterial infection, patients should be told that although it is common to feel better early in
the course of therapy, the medication should be taken exactly as directed. Skipping doses or not completing the full
course of therapy may (1) decrease the effectiveness of the immediate treatment and (2) increase the likelihood that
bacteria will develop resistance and will not be treatable by Macrobid or other antibacterial drugs in the
future.
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Organismes affectes
Gram négatif et certaines bactéries Gram positives