cetohyroxamic acid
Brand names,
cetohyroxamic acid
Analogs
cetohyroxamic acid
Brand Names Mixture
cetohyroxamic acid
Chemical_Formula
C2H5NO2
cetohyroxamic acid
RX_link
No information avaliable
cetohyroxamic acid
fda sheet
cetohyroxamic acid
msds (material safety sheet)
cetohyroxamic acid
Synthesis Reference
No information avaliable
cetohyroxamic acid
Molecular Weight
75.0666 g/mol
cetohyroxamic acid
Melting Point
90.5 oC
cetohyroxamic acid
H2O Solubility
1E+006 mg/L
cetohyroxamic acid
State
Solid
cetohyroxamic acid
LogP
-0.564
cetohyroxamic acid
Dosage Forms
Tablet (250mg)
cetohyroxamic acid
Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
cetohyroxamic acid
Pharmacology
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
cetohyroxamic acid
Absorption
Well absorbed from the GI tract following oral administration.
cetohyroxamic acid
side effects and Toxicity
Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
cetohyroxamic acid
Patient Information
No information avaliable
cetohyroxamic acid
Organisms Affected
Enteric bacteria and other eubacteria