N-Hydroxyacetamide
N-Hydroxyacetamide Brand names, N-Hydroxyacetamide Analogs
N-Hydroxyacetamide Brand Names Mixture
- No information avaliable
N-Hydroxyacetamide Chemical_Formula
C2H5NO2
N-Hydroxyacetamide RX_link
No information avaliable
N-Hydroxyacetamide fda sheet
N-Hydroxyacetamide msds (material safety sheet)
N-Hydroxyacetamide Synthesis Reference
No information avaliable
N-Hydroxyacetamide Molecular Weight
75.0666 g/mol
N-Hydroxyacetamide Melting Point
90.5 oC
N-Hydroxyacetamide H2O Solubility
1E+006 mg/L
N-Hydroxyacetamide State
Solid
N-Hydroxyacetamide LogP
-0.564
N-Hydroxyacetamide Dosage Forms
Tablet (250mg)
N-Hydroxyacetamide Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
N-Hydroxyacetamide Pharmacology
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
N-Hydroxyacetamide Absorption
Well absorbed from the GI tract following oral administration.
N-Hydroxyacetamide side effects and Toxicity
Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
N-Hydroxyacetamide Patient Information
No information avaliable
N-Hydroxyacetamide Organisms Affected
Enteric bacteria and other eubacteria
