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Brand names,
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Analogs
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Brand Names Mixture
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Chemical_Formula
C2H5NO2
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RX_link
No information avaliable
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fda sheet
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msds (material safety sheet)
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Synthesis Reference
No information avaliable
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Molecular Weight
75.0666 g/mol
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Melting Point
90.5 oC
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H2O Solubility
1E+006 mg/L
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State
Solid
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LogP
-0.564
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Dosage Forms
Tablet (250mg)
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Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
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Pharmacology
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
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Absorption
Well absorbed from the GI tract following oral administration.
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side effects and Toxicity
Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
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Patient Information
No information avaliable
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Organisms Affected
Enteric bacteria and other eubacteria