Acetylhydroxamic acid
Brand names,
Acetylhydroxamic acid
Analogs
Acetylhydroxamic acid
Brand Names Mixture
Acetylhydroxamic acid
Chemical_Formula
C2H5NO2
Acetylhydroxamic acid
RX_link
No information avaliable
Acetylhydroxamic acid
fda sheet
Acetylhydroxamic acid
msds (material safety sheet)
Acetylhydroxamic acid
Synthesis Reference
No information avaliable
Acetylhydroxamic acid
Molecular Weight
75.0666 g/mol
Acetylhydroxamic acid
Melting Point
90.5 oC
Acetylhydroxamic acid
H2O Solubility
1E+006 mg/L
Acetylhydroxamic acid
State
Solid
Acetylhydroxamic acid
LogP
-0.564
Acetylhydroxamic acid
Dosage Forms
Tablet (250mg)
Acetylhydroxamic acid
Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Acetylhydroxamic acid
Pharmacology
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
Acetylhydroxamic acid
Absorption
Well absorbed from the GI tract following oral administration.
Acetylhydroxamic acid
side effects and Toxicity
Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
Acetylhydroxamic acid
Patient Information
No information avaliable
Acetylhydroxamic acid
Organisms Affected
Enteric bacteria and other eubacteria