Acetohydroximic acid
Brand names,
Acetohydroximic acid
Analogs
Acetohydroximic acid
Brand Names Mixture
Acetohydroximic acid
Chemical_Formula
C2H5NO2
Acetohydroximic acid
RX_link
No information avaliable
Acetohydroximic acid
fda sheet
Acetohydroximic acid
msds (material safety sheet)
Acetohydroximic acid
Synthesis Reference
No information avaliable
Acetohydroximic acid
Molecular Weight
75.0666 g/mol
Acetohydroximic acid
Melting Point
90.5 oC
Acetohydroximic acid
H2O Solubility
1E+006 mg/L
Acetohydroximic acid
State
Solid
Acetohydroximic acid
LogP
-0.564
Acetohydroximic acid
Dosage Forms
Tablet (250mg)
Acetohydroximic acid
Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Acetohydroximic acid
Pharmacology
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
Acetohydroximic acid
Absorption
Well absorbed from the GI tract following oral administration.
Acetohydroximic acid
side effects and Toxicity
Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
Acetohydroximic acid
Patient Information
No information avaliable
Acetohydroximic acid
Organisms Affected
Enteric bacteria and other eubacteria