Lithostat
Brand names,
Lithostat
Analogs
Lithostat
Brand Names Mixture
Lithostat
Chemical_Formula
C2H5NO2
Lithostat
RX_link
No information avaliable
Lithostat
fda sheet
Lithostat
msds (material safety sheet)
Lithostat
Synthesis Reference
No information avaliable
Lithostat
Molecular Weight
75.0666 g/mol
Lithostat
Melting Point
90.5 oC
Lithostat
H2O Solubility
1E+006 mg/L
Lithostat
State
Solid
Lithostat
LogP
-0.564
Lithostat
Dosage Forms
Tablet (250mg)
Lithostat
Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Lithostat
Pharmacology
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
Lithostat
Absorption
Well absorbed from the GI tract following oral administration.
Lithostat
side effects and Toxicity
Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
Lithostat
Patient Information
No information avaliable
Lithostat
Organisms Affected
Enteric bacteria and other eubacteria