Methylhydroxamic acid
Brand names,
Methylhydroxamic acid
Analogs
Methylhydroxamic acid
Brand Names Mixture
Methylhydroxamic acid
Chemical_Formula
C2H5NO2
Methylhydroxamic acid
RX_link
No information avaliable
Methylhydroxamic acid
fda sheet
Methylhydroxamic acid
msds (material safety sheet)
Methylhydroxamic acid
Synthesis Reference
No information avaliable
Methylhydroxamic acid
Molecular Weight
75.0666 g/mol
Methylhydroxamic acid
Melting Point
90.5 oC
Methylhydroxamic acid
H2O Solubility
1E+006 mg/L
Methylhydroxamic acid
State
Solid
Methylhydroxamic acid
LogP
-0.564
Methylhydroxamic acid
Dosage Forms
Tablet (250mg)
Methylhydroxamic acid
Indication
Used, in addition to antibiotics or medical procedures, to treat chronic urea-splitting urinary infections.
Methylhydroxamic acid
Pharmacology
Acetohydroxamic Acid, a synthetic drug derived from hydroxylamine and ethyl acetate, is similar in structure to urea. In the urine, it acts as an antagonist of the bacterial enzyme urease. Acetohydroxamic Acid has no direct antimicrobial action and does not acidify urine directly.
Methylhydroxamic acid
Absorption
Well absorbed from the GI tract following oral administration.
Methylhydroxamic acid
side effects and Toxicity
Oral, rat: LD50 = 4.8gm/kg. Symptoms of overdose include anorexia, malaise, lethargy, diminished sense of wellbeing, tremor, anxiety, nausea, and vomiting.
Methylhydroxamic acid
Patient Information
No information avaliable
Methylhydroxamic acid
Organisms Affected
Enteric bacteria and other eubacteria