Vincaleucoblastin

Vincaleucoblastin Brand names, Vincaleucoblastin Analogs

Vincaleucoblastin Brand Names Mixture

No information avaliable

Vincaleucoblastin Chemical_Formula

C₄₆H₅₈N₄O₉

Vincaleucoblastin RX_link

http://www.rxlist.com/cgi/generic3/vinblastine.htm

Vincaleucoblastin fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=29

Vincaleucoblastin msds (material safety sheet)

Vincaleucoblastin MSDS

Vincaleucoblastin Synthesis Reference

No information avaliable

Vincaleucoblastin Molecular Weight

810.974 g/mol

Vincaleucoblastin Melting Point

267 ^oC

Vincaleucoblastin H₂O Solubility

Negligible

Vincaleucoblastin State

Solid

Vincaleucoblastin LogP

5.587

Vincaleucoblastin Dosage Forms

Liquid; Powder for solution; Solution

Vincaleucoblastin Indication

For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.

Vincaleucoblastin Pharmacology

Vinblastine is a vinca alkaloid antineoplastic agent. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units: vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinblastine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Vincaleucoblastin Absorption