Vinblastine Sulfate

Vinblastine Sulfate Brand names, Vinblastine Sulfate Analogs

Vinblastine Sulfate Brand Names Mixture

No information avaliable

Vinblastine Sulfate Chemical_Formula

C₄₆H₅₈N₄O₉

Vinblastine Sulfate RX_link

http://www.rxlist.com/cgi/generic3/vinblastine.htm

Vinblastine Sulfate fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=29

Vinblastine Sulfate msds (material safety sheet)

Vinblastine_Sulfate MSDS

Vinblastine Sulfate Synthesis Reference

No information avaliable

Vinblastine Sulfate Molecular Weight

810.974 g/mol

Vinblastine Sulfate Melting Point

267 ^oC

Vinblastine Sulfate H₂O Solubility

Negligible

Vinblastine Sulfate State

Solid

Vinblastine Sulfate LogP

5.587

Vinblastine Sulfate Dosage Forms

Liquid; Powder for solution; Solution

Vinblastine Sulfate Indication

For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.

Vinblastine Sulfate Pharmacology

Vinblastine is a vinca alkaloid antineoplastic agent. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units: vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinblastine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Vinblastine Sulfate Absorption