Velban

Velban Brand names, Velban Analogs

Velban Brand Names Mixture

No information avaliable

Velban Chemical_Formula

C₄₆H₅₈N₄O₉

Velban RX_link

http://www.rxlist.com/cgi/generic3/vinblastine.htm

Velban fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=29

Velban msds (material safety sheet)

Velban MSDS

Velban Synthesis Reference

No information avaliable

Velban Molecular Weight

810.974 g/mol

Velban Melting Point

267 ^oC

Velban H₂O Solubility

Negligible

Velban State

Solid

Velban LogP

5.587

Velban Dosage Forms

Liquid; Powder for solution; Solution

Velban Indication

For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.

Velban Pharmacology

Vinblastine is a vinca alkaloid antineoplastic agent. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units: vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinblastine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Velban Absorption