Velbe

Velbe Brand names, Velbe Analogs

Velbe Brand Names Mixture

No information avaliable

Velbe Chemical_Formula

C₄₆H₅₈N₄O₉

Velbe RX_link

http://www.rxlist.com/cgi/generic3/vinblastine.htm

Velbe fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=29

Velbe msds (material safety sheet)

Velbe MSDS

Velbe Synthesis Reference

No information avaliable

Velbe Molecular Weight

810.974 g/mol

Velbe Melting Point

267 ^oC

Velbe H₂O Solubility

Negligible

Velbe State

Solid

Velbe LogP

5.587

Velbe Dosage Forms

Liquid; Powder for solution; Solution

Velbe Indication

For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.

Velbe Pharmacology

Vinblastine is a vinca alkaloid antineoplastic agent. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units: vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinblastine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Velbe Absorption