Rozevin

Rozevin Brand names, Rozevin Analogs

Rozevin Brand Names Mixture

No information avaliable

Rozevin Chemical_Formula

C₄₆H₅₈N₄O₉

Rozevin RX_link

http://www.rxlist.com/cgi/generic3/vinblastine.htm

Rozevin fda sheet

http://www.accessdata.fda.gov/scripts/cder/onctools/summary.cfm?ID=29

Rozevin msds (material safety sheet)

Rozevin MSDS

Rozevin Synthesis Reference

No information avaliable

Rozevin Molecular Weight

810.974 g/mol

Rozevin Melting Point

267 ^oC

Rozevin H₂O Solubility

Negligible

Rozevin State

Solid

Rozevin LogP

5.587

Rozevin Dosage Forms

Liquid; Powder for solution; Solution

Rozevin Indication

For treatment of breast cancer, testicular cancer, lymphomas, neuroblastoma, Hodgkin's and non-Hodgkin's lymphomas, mycosis fungoides, histiocytosis, and Kaposi's sarcoma.

Rozevin Pharmacology

Vinblastine is a vinca alkaloid antineoplastic agent. The vinca alkaloids are structurally similar compounds comprised of 2 multiringed units: vindoline and catharanthine. The vinca alkaloids have become clinically useful since the discovery of their antitumour properties in 1959. Initially, extracts of the periwinkle plant (Catharanthus roseus) were investigated because of putative hypoglycemic properties, but were noted to cause marrow suppression in rats and antileukemic effects in vitro. Vinblastine has some immunosuppressant effect. The vinca alkaloids are considered to be cell cycle phase-specific.

Rozevin Absorption