Tonaril
Brand names,
Tonaril
Analogs
Tonaril
Brand Names Mixture
Tonaril
Chemical_Formula
C16H21N3
Tonaril
RX_link
No information avaliable
Tonaril
fda sheet
Tonaril
msds (material safety sheet)
Tonaril
Synthesis Reference
No information avaliable
Tonaril
Molecular Weight
255.358 g/mol
Tonaril
Melting Point
No information avaliable
Tonaril
H2O Solubility
587 mg/L
Tonaril
State
Solid
Tonaril
LogP
2.646
Tonaril
Dosage Forms
Cream; Liquid; Tablet
Tonaril
Indication
Used for the symptomatic relief of hypersensitivity reactions, coughs, and the common cold.
Tonaril
Pharmacology
Used to treat the effects of colds and allergies. Tripelennamine is an antihistamine. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Tripelennamine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Tonaril
Absorption
Well absorbed in the digestive tract.
Tonaril
side effects and Toxicity
Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands and trouble in sleeping.
Tonaril
Patient Information
Tonaril
Organisms Affected
Humans and other mammals