Pyribenzamine
Brand names,
Pyribenzamine
Analogs
Pyribenzamine
Brand Names Mixture
Pyribenzamine
Chemical_Formula
C16H21N3
Pyribenzamine
RX_link
No information avaliable
Pyribenzamine
fda sheet
Pyribenzamine
msds (material safety sheet)
Pyribenzamine
Synthesis Reference
No information avaliable
Pyribenzamine
Molecular Weight
255.358 g/mol
Pyribenzamine
Melting Point
No information avaliable
Pyribenzamine
H2O Solubility
587 mg/L
Pyribenzamine
State
Solid
Pyribenzamine
LogP
2.646
Pyribenzamine
Dosage Forms
Cream; Liquid; Tablet
Pyribenzamine
Indication
Used for the symptomatic relief of hypersensitivity reactions, coughs, and the common cold.
Pyribenzamine
Pharmacology
Used to treat the effects of colds and allergies. Tripelennamine is an antihistamine. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Tripelennamine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Pyribenzamine
Absorption
Well absorbed in the digestive tract.
Pyribenzamine
side effects and Toxicity
Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands and trouble in sleeping.
Pyribenzamine
Patient Information
Pyribenzamine
Organisms Affected
Humans and other mammals