Dehistin
Brand names,
Dehistin
Analogs
Dehistin
Brand Names Mixture
Dehistin
Chemical_Formula
C16H21N3
Dehistin
RX_link
No information avaliable
Dehistin
fda sheet
Dehistin
msds (material safety sheet)
Dehistin
Synthesis Reference
No information avaliable
Dehistin
Molecular Weight
255.358 g/mol
Dehistin
Melting Point
No information avaliable
Dehistin
H2O Solubility
587 mg/L
Dehistin
State
Solid
Dehistin
LogP
2.646
Dehistin
Dosage Forms
Cream; Liquid; Tablet
Dehistin
Indication
Used for the symptomatic relief of hypersensitivity reactions, coughs, and the common cold.
Dehistin
Pharmacology
Used to treat the effects of colds and allergies. Tripelennamine is an antihistamine. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Tripelennamine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Dehistin
Absorption
Well absorbed in the digestive tract.
Dehistin
side effects and Toxicity
Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands and trouble in sleeping.
Dehistin
Patient Information
Dehistin
Organisms Affected
Humans and other mammals