Pyrinamine Base
Brand names,
Pyrinamine Base
Analogs
Pyrinamine Base
Brand Names Mixture
Pyrinamine Base
Chemical_Formula
C16H21N3
Pyrinamine Base
RX_link
No information avaliable
Pyrinamine Base
fda sheet
Pyrinamine Base
msds (material safety sheet)
Pyrinamine Base
Synthesis Reference
No information avaliable
Pyrinamine Base
Molecular Weight
255.358 g/mol
Pyrinamine Base
Melting Point
No information avaliable
Pyrinamine Base
H2O Solubility
587 mg/L
Pyrinamine Base
State
Solid
Pyrinamine Base
LogP
2.646
Pyrinamine Base
Dosage Forms
Cream; Liquid; Tablet
Pyrinamine Base
Indication
Used for the symptomatic relief of hypersensitivity reactions, coughs, and the common cold.
Pyrinamine Base
Pharmacology
Used to treat the effects of colds and allergies. Tripelennamine is an antihistamine. Histamine, acting on H1-receptors, produces pruritis, vasodilatation, hypotension, flushing, headache, tachycardia, and bronchoconstriction. Histamine also increases vascular permeability and potentiates pain. Tripelennamine is a histamine H1 antagonist. It competes with histamine for the normal H1-receptor sites on effector cells of the gastrointestinal tract, blood vessels and respiratory tract. It provides effective, temporary relief of sneezing, watery and itchy eyes, and runny nose due to hay fever and other upper respiratory allergies.
Pyrinamine Base
Absorption
Well absorbed in the digestive tract.
Pyrinamine Base
side effects and Toxicity
Symptoms of overdose include clumsiness or unsteadiness, convulsions, drowsiness, dryness of mouth, nose, or throat, feeling faint, flushing or redness of face, hallucinations, muscle spasms (especially of neck and back), restlessness, shortness of breath or troubled breathing, shuffling walk, tic-like movements of head and face, trembling and shaking of hands and trouble in sleeping.
Pyrinamine Base
Patient Information
Pyrinamine Base
Organisms Affected
Humans and other mammals