Thioconazole
Brand names,
Thioconazole
Analogs
Thioconazole
Brand Names Mixture
Thioconazole
Chemical_Formula
C18H13Cl4N3O
Thioconazole
RX_link
http://www.rxlist.com/cgi/generic3/oxico.htm
Thioconazole
fda sheet
Thioconazole
msds (material safety sheet)
Thioconazole
Synthesis Reference
No information avaliable
Thioconazole
Molecular Weight
429.126 g/mol
Thioconazole
Melting Point
No information avaliable
Thioconazole
H2O Solubility
No information avaliable
Thioconazole
State
Solid
Thioconazole
LogP
5.983
Thioconazole
Dosage Forms
Cream; Lotion
Thioconazole
Indication
For treatment of dermal fungal infection.
Thioconazole
Pharmacology
Oxiconazole nitrate is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has fungicidal or fungistatic activity in vitro against a number of pathogenic fungi including the following dermatophytes, and yeasts: T. rubrum, T. mentagrophytes, T. tonsurans, T. violaceum, E. floccosum, M. canis, M. audouini, M. gypseum, C. albicans, and M. furfur.
Thioconazole
Absorption
Systemic absorption of oxiconazole nitrate is low.
Thioconazole
side effects and Toxicity
Side effects incliude pruritus, burning, irritation, erythema, stinging and allergic contact dermatitis and folliculitis, fissuring, maceration rash and nodules.
Thioconazole
Patient Information
Thioconazole
Organisms Affected
Fungi