Oxistat
Oxistat Brand names, Oxistat Analogs
Oxistat Brand Names Mixture
- No information avaliable
Oxistat Chemical_Formula
C18H13Cl4N3O
Oxistat RX_link
http://www.rxlist.com/cgi/generic3/oxico.htm
Oxistat fda sheet
Oxistat msds (material safety sheet)
Oxistat Synthesis Reference
No information avaliable
Oxistat Molecular Weight
429.126 g/mol
Oxistat Melting Point
No information avaliable
Oxistat H2O Solubility
No information avaliable
Oxistat State
Solid
Oxistat LogP
5.983
Oxistat Dosage Forms
Cream; Lotion
Oxistat Indication
For treatment of dermal fungal infection.
Oxistat Pharmacology
Oxiconazole nitrate is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has fungicidal or fungistatic activity in vitro against a number of pathogenic fungi including the following dermatophytes, and yeasts: T. rubrum, T. mentagrophytes, T. tonsurans, T. violaceum, E. floccosum, M. canis, M. audouini, M. gypseum, C. albicans, and M. furfur.
Oxistat Absorption
Systemic absorption of oxiconazole nitrate is low.
Oxistat side effects and Toxicity
Side effects incliude pruritus, burning, irritation, erythema, stinging and allergic contact dermatitis and folliculitis, fissuring, maceration rash and nodules.
Oxistat Patient Information
Oxistat Organisms Affected
Fungi
