Oxiconazolc Nitrate
Brand names,
Oxiconazolc Nitrate
Analogs
Oxiconazolc Nitrate
Brand Names Mixture
Oxiconazolc Nitrate
Chemical_Formula
C18H13Cl4N3O
Oxiconazolc Nitrate
RX_link
http://www.rxlist.com/cgi/generic3/oxico.htm
Oxiconazolc Nitrate
fda sheet
Oxiconazolc Nitrate
msds (material safety sheet)
Oxiconazolc Nitrate
Synthesis Reference
No information avaliable
Oxiconazolc Nitrate
Molecular Weight
429.126 g/mol
Oxiconazolc Nitrate
Melting Point
No information avaliable
Oxiconazolc Nitrate
H2O Solubility
No information avaliable
Oxiconazolc Nitrate
State
Solid
Oxiconazolc Nitrate
LogP
5.983
Oxiconazolc Nitrate
Dosage Forms
Cream; Lotion
Oxiconazolc Nitrate
Indication
For treatment of dermal fungal infection.
Oxiconazolc Nitrate
Pharmacology
Oxiconazole nitrate is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has fungicidal or fungistatic activity in vitro against a number of pathogenic fungi including the following dermatophytes, and yeasts: T. rubrum, T. mentagrophytes, T. tonsurans, T. violaceum, E. floccosum, M. canis, M. audouini, M. gypseum, C. albicans, and M. furfur.
Oxiconazolc Nitrate
Absorption
Systemic absorption of oxiconazole nitrate is low.
Oxiconazolc Nitrate
side effects and Toxicity
Side effects incliude pruritus, burning, irritation, erythema, stinging and allergic contact dermatitis and folliculitis, fissuring, maceration rash and nodules.
Oxiconazolc Nitrate
Patient Information
Oxiconazolc Nitrate
Organisms Affected
Fungi