Oxiconazolum [INN-Latin]
Brand names,
Oxiconazolum [INN-Latin]
Analogs
Oxiconazolum [INN-Latin]
Brand Names Mixture
Oxiconazolum [INN-Latin]
Chemical_Formula
C18H13Cl4N3O
Oxiconazolum [INN-Latin]
RX_link
http://www.rxlist.com/cgi/generic3/oxico.htm
Oxiconazolum [INN-Latin]
fda sheet
Oxiconazolum [INN-Latin]
msds (material safety sheet)
Oxiconazolum [INN-Latin]
Synthesis Reference
No information avaliable
Oxiconazolum [INN-Latin]
Molecular Weight
429.126 g/mol
Oxiconazolum [INN-Latin]
Melting Point
No information avaliable
Oxiconazolum [INN-Latin]
H2O Solubility
No information avaliable
Oxiconazolum [INN-Latin]
State
Solid
Oxiconazolum [INN-Latin]
LogP
5.983
Oxiconazolum [INN-Latin]
Dosage Forms
Cream; Lotion
Oxiconazolum [INN-Latin]
Indication
For treatment of dermal fungal infection.
Oxiconazolum [INN-Latin]
Pharmacology
Oxiconazole nitrate is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has fungicidal or fungistatic activity in vitro against a number of pathogenic fungi including the following dermatophytes, and yeasts: T. rubrum, T. mentagrophytes, T. tonsurans, T. violaceum, E. floccosum, M. canis, M. audouini, M. gypseum, C. albicans, and M. furfur.
Oxiconazolum [INN-Latin]
Absorption
Systemic absorption of oxiconazole nitrate is low.
Oxiconazolum [INN-Latin]
side effects and Toxicity
Side effects incliude pruritus, burning, irritation, erythema, stinging and allergic contact dermatitis and folliculitis, fissuring, maceration rash and nodules.
Oxiconazolum [INN-Latin]
Patient Information
Oxiconazolum [INN-Latin]
Organisms Affected
Fungi