Oxiconazole
Brand names,
Oxiconazole
Analogs
Oxiconazole
Brand Names Mixture
Oxiconazole
Chemical_Formula
C18H13Cl4N3O
Oxiconazole
RX_link
http://www.rxlist.com/cgi/generic3/oxico.htm
Oxiconazole
fda sheet
Oxiconazole
msds (material safety sheet)
Oxiconazole
Synthesis Reference
No information avaliable
Oxiconazole
Molecular Weight
429.126 g/mol
Oxiconazole
Melting Point
No information avaliable
Oxiconazole
H2O Solubility
No information avaliable
Oxiconazole
State
Solid
Oxiconazole
LogP
5.983
Oxiconazole
Dosage Forms
Cream; Lotion
Oxiconazole
Indication
For treatment of dermal fungal infection.
Oxiconazole
Pharmacology
Oxiconazole nitrate is a broad-spectrum imidazole derivative whose antifungal activity is derived primarily from the inhibition of ergosterol biosynthesis, which is critical for cellular membrane integrity. It has fungicidal or fungistatic activity in vitro against a number of pathogenic fungi including the following dermatophytes, and yeasts: T. rubrum, T. mentagrophytes, T. tonsurans, T. violaceum, E. floccosum, M. canis, M. audouini, M. gypseum, C. albicans, and M. furfur.
Oxiconazole
Absorption
Systemic absorption of oxiconazole nitrate is low.
Oxiconazole
side effects and Toxicity
Side effects incliude pruritus, burning, irritation, erythema, stinging and allergic contact dermatitis and folliculitis, fissuring, maceration rash and nodules.
Oxiconazole
Patient Information
Oxiconazole
Organisms Affected
Fungi