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Terfex Brand names, Terfex Analogs

Terfex Brand Names Mixture

  • No information avaliable

Terfex Chemical_Formula


Terfex RX_link


Terfex fda sheet

Terfex msds (material safety sheet)

Terfex Synthesis Reference

A. A. Carr, C. R. Kinsolving, U.S. Pat. 3,878,217 (1975)

Terfex Molecular Weight

471.673 g/mol

Terfex Melting Point


Terfex H2O Solubility

10 mg/L

Terfex State


Terfex LogP


Terfex Dosage Forms

Oral tablets

Terfex Indication

For the treatment of allergic rhinitis, hay fever, and allergic skin disorders.

Terfex Pharmacology

Terfenadine, an H1-receptor antagonist antihistamine, is similar in structure to astemizole and haloperidol, a butyrophenone antipsychotic. The active metabolite of terfenadine is fexofenadine.

Terfex Absorption

On the basis of a mass balance study using 14C labeled terfenadine the oral absorption of terfenadine was estimated to be at least 70%

Terfex side effects and Toxicity

Mild (e.g., headache, nausea, confusion), but adverse cardiac events including cardiac arrest, ventricular arrhythmias including torsades de pointes and QT prolongation have been reported. LD50=mg/kg (orally in mice)

Terfex Patient Information

Terfex Organisms Affected

Humans and other mammals