Seldane en es it fr

Seldane Brand names, Seldane Analogs

Seldane Brand Names Mixture

  • No information avaliable

Seldane Chemical_Formula


Seldane RX_link

Seldane fda sheet

Seldane msds (material safety sheet)

Seldane Synthesis Reference

A. A. Carr, C. R. Kinsolving, U.S. Pat. 3,878,217 (1975)

Seldane Molecular Weight

471.673 g/mol

Seldane Melting Point


Seldane H2O Solubility

10 mg/L

Seldane State


Seldane LogP


Seldane Dosage Forms

Oral tablets

Seldane Indication

For the treatment of allergic rhinitis, hay fever, and allergic skin disorders.

Seldane Pharmacology

Terfenadine, an H1-receptor antagonist antihistamine, is similar in structure to astemizole and haloperidol, a butyrophenone antipsychotic. The active metabolite of terfenadine is fexofenadine.

Seldane Absorption

On the basis of a mass balance study using 14C labeled terfenadine the oral absorption of terfenadine was estimated to be at least 70%

Seldane side effects and Toxicity

Mild (e.g., headache, nausea, confusion), but adverse cardiac events including cardiac arrest, ventricular arrhythmias including torsades de pointes and QT prolongation have been reported. LD50=mg/kg (orally in mice)

Seldane Patient Information

Seldane Organisms Affected

Humans and other mammals