Terdin

Terdin Brand names, Terdin Analogs

Terdin Brand Names Mixture

No information avaliable

Terdin Chemical_Formula

C₃₂H₄₁NO₂

Terdin RX_link

http://www.rxlist.com/cgi/generic/terfen.htm

Terdin fda sheet

Terdin msds (material safety sheet)

Terdin Synthesis Reference

A. A. Carr, C. R. Kinsolving, U.S. Pat. 3,878,217 (1975)

Terdin Molecular Weight

471.673 g/mol

Terdin Melting Point

146.5-148.5^oC

Terdin H₂O Solubility

10 mg/L

Terdin State

Solid

Terdin LogP

7.784

Terdin Dosage Forms

Oral tablets

Terdin Indication

For the treatment of allergic rhinitis, hay fever, and allergic skin disorders.

Terdin Pharmacology

Terfenadine, an H1-receptor antagonist antihistamine, is similar in structure to astemizole and haloperidol, a butyrophenone antipsychotic. The active metabolite of terfenadine is fexofenadine.

Terdin Absorption

On the basis of a mass balance study using 14C labeled terfenadine the oral absorption of terfenadine was estimated to be at least 70%

Terdin side effects and Toxicity

Mild (e.g., headache, nausea, confusion), but adverse cardiac events including cardiac arrest, ventricular arrhythmias including torsades de pointes and QT prolongation have been reported. LD₅₀=mg/kg (orally in mice)

Terdin Patient Information

Terdin Organisms Affected

Humans and other mammals