PharmacyCodes



Aldaban en es it fr

Aldaban Brand names, Aldaban Analogs

Aldaban Brand Names Mixture

  • No information avaliable

Aldaban Chemical_Formula

C32H41NO2

Aldaban RX_link

http://www.rxlist.com/cgi/generic/terfen.htm

Aldaban fda sheet

Aldaban msds (material safety sheet)

Aldaban Synthesis Reference

A. A. Carr, C. R. Kinsolving, U.S. Pat. 3,878,217 (1975)

Aldaban Molecular Weight

471.673 g/mol

Aldaban Melting Point

146.5-148.5oC

Aldaban H2O Solubility

10 mg/L

Aldaban State

Solid

Aldaban LogP

7.784

Aldaban Dosage Forms

Oral tablets

Aldaban Indication

For the treatment of allergic rhinitis, hay fever, and allergic skin disorders.

Aldaban Pharmacology

Terfenadine, an H1-receptor antagonist antihistamine, is similar in structure to astemizole and haloperidol, a butyrophenone antipsychotic. The active metabolite of terfenadine is fexofenadine.

Aldaban Absorption

On the basis of a mass balance study using 14C labeled terfenadine the oral absorption of terfenadine was estimated to be at least 70%

Aldaban side effects and Toxicity

Mild (e.g., headache, nausea, confusion), but adverse cardiac events including cardiac arrest, ventricular arrhythmias including torsades de pointes and QT prolongation have been reported. LD50=mg/kg (orally in mice)

Aldaban Patient Information

Aldaban Organisms Affected

Humans and other mammals