Teldanex
Teldanex Brand names, Teldanex Analogs
Teldanex Brand Names Mixture
- No information avaliable
Teldanex Chemical_Formula
C32H41NO2
Teldanex RX_link
http://www.rxlist.com/cgi/generic/terfen.htm
Teldanex fda sheet
Teldanex msds (material safety sheet)
Teldanex Synthesis Reference
A. A. Carr, C. R. Kinsolving, U.S. Pat. 3,878,217 (1975)
Teldanex Molecular Weight
471.673 g/mol
Teldanex Melting Point
146.5-148.5oC
Teldanex H2O Solubility
10 mg/L
Teldanex State
Solid
Teldanex LogP
7.784
Teldanex Dosage Forms
Oral tablets
Teldanex Indication
For the treatment of allergic rhinitis, hay fever, and allergic skin disorders.
Teldanex Pharmacology
Terfenadine, an H1-receptor antagonist antihistamine, is similar in structure to astemizole and haloperidol, a butyrophenone antipsychotic. The active metabolite of terfenadine is fexofenadine.
Teldanex Absorption
On the basis of a mass balance study using 14C labeled terfenadine the oral absorption of terfenadine was estimated to be at least 70%
Teldanex side effects and Toxicity
Mild (e.g., headache, nausea, confusion), but adverse cardiac events including cardiac arrest, ventricular arrhythmias including torsades de pointes and QT prolongation have been reported. LD50=mg/kg (orally in mice)
Teldanex Patient Information
Teldanex Organisms Affected
Humans and other mammals
